rational drug design

基本解釋

The rational drug design is based on the detailed knowledge of the action mechanism.
合理進(jìn)行藥物分子設(shè)計(jì)的前提是對(duì)藥物—靶分子作用機(jī)制有深入的了解。
Molecular docking is to study the interaction between the ligand and the receptor and plays a important role in rational drug design.
分子對(duì)接是研究配體與受體之間相互作用及虛擬篩選的有效工具，在藥物合理設(shè)計(jì)中起著非常重要的作用。
Computer-aided molecular design (CAMD) is now an uprising subject in medicinal chemistry among which structure-based rational drug design is attracting more and more attention.
計(jì)算機(jī)輔助藥物分子設(shè)計(jì)近年來(lái)已成為新藥創(chuàng)制的重要手段。基于結(jié)構(gòu)的合理藥物分子設(shè)計(jì)則是多學(xué)科交互融合和滲透的體現(xiàn)。

Rational drug design, the hallmark of new-school biotech, is no panacea, as Gladwell rightly points out.
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The drug was originally developed as Imatinib using rational drug design after Philadelphia chromosome mutation was discovered.
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